Sistema de liberación oral controlada

Controlled Release Delivery System

During manufacturing, through a specific technological process the oral control release system simplifies the oral administration of the medicine that release gradually and steadily its active ingredients.

Benefits:

  • Decreases daily dosage (better therapeutic adherence).
  • Uniform and steady therapeutic levels.
  • Increases the plasma concentrations of short half-life active ingredients.
  • Combination of active ingredients with different release profiles in the same medicine.
  • pH independence (consistent release)
  • Protection of the active ingredient against gastric pH

 

RELEASE TECHNOLOGY

TR–Caps: Time release pellets

IR–Caps: Immediate release pellets

GR–Caps: Gastro resistant pellets

 

 

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Graph Number 1: Study of Bioavailability Nifedipine 30mg 24 hours. Source: Study of Bioavailability of Nifedipine 24 hours, Protocol BD100329-001, 03/29/2010.
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